Executive Director Drug Design

  • Exscientia
  • Oxford, UK
  • 15/10/2020
Full time Data Science Data Analytics Big Data Data Management Statistics

Job Description

Exscientia is at the forefront of Artificial Intelligence (AI) driven drug discovery and the only company to successfully design drug molecules entirely by AI that are in clinical studies. As a full stack AI Pharmatech, we utilise all available information sources, combine with our own experimental data and exploit with the analytical power of AI and the creativity and expertise of our world-class scientists. We aim to revolutionise the pharmaceutical industry by significantly shortening the preclinical drug discovery stage to accelerate new treatments to patients globally. Exscientia is looking for extraordinary people to join its extraordinary mission: to revolutionise the way new medicines are discovered.Following multiple high-profile partnerships and our most recent fundraise we are now adding key appointments to our group – Executive Director Drug Design. Reporting to SVP, Head of Drug Design, these positions are integral to support and build the Company’s drug discovery pipeline as it executes the next phase of its life cycle. We are looking for proven drug hunters to join our design team.Leading multiple drug discovery programmes you will work closely with Computational Designers to set overall strategic objectives (including contribution to asset product profiles) and be responsible for the delivery of lead and candidate milestones.Through analysis of test results, you will propose design criteria for each iteration as well as working within project core teams to identify appropriate assays for further evaluation of current lead molecules. In collaboration with design team members you will identify sets of new molecular targets for completion by synthetic teams within preferred CROs or our external collaborators.The influence of this position extends beyond Exscientia’s drug discovery portfolio. Suitable candidates will be expected to work closely with the technology development team to identify and define key platform improvements. In addition, you will provide medicinal chemistry input on potential new biological targets to support decisions on their inclusion in the Exscientia portfolio (e.g. tractability, strategic approach, hit-finding strategies).Finally, as a seasoned drug hunter, you will provide mentorship to less experienced project team members as they build their medicinal chemistry careers within Exscientia.

What will you bring to the role?

  • Educated to PhD level with 10+ years’ experience of industrial medicinal chemistry
  • Highly motivated with a track record of candidate delivery
  • Embrace modern drug discovery technologies and enthusiasm to apply algorithm-derived compound designs
  • Working proficiency and communication skills in verbal and written English

Desirable Skills

  • Domain knowledge in medicinal computational chemistry or structural biology as applied to contemporary drug discovery
  • Prior involvement with late pre-clinical teams

What can you expect from us?

  • An opportunity to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI driven discovery
  • The ability to strongly influence a scaling AI organisation with world class technical and scientific leaders
  • An opportunity to grow your career with us as we grow our organisation
  • A highly competitive compensation package to support our employees as we continue to grow and thrive
  • The opportunity to join an inclusive, collaborative and intellectually stimulating culture