ChemInformatician

  • AstraZeneca
  • Cambridge CB2 8PA, UK
  • 28/05/2021
Full time Data Science Data Engineering Data Analytics Big Data Data Management Statistics

Job Description

ABOUT ASTRAZENECA

AstraZeneca is a global, innovation-driven BioPharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious disease. But we’re more than one of the world’s leading pharmaceutical companies.

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

ABOUT OUR IT TEAM

Here our work has a direct impact on patients – transforming our ability to develop life-changing medicines. We empower the business to perform at its peak and lead a new way of working, combining cutting-edge science with leading digital technology platforms and data. All with a passion to impact lives through data, analytics, AI, machine learning and more. Join us at a crucial stage of our journey in becoming a digital and data-led enterprise. Make the impossible possible by building partnerships and ecosystems, creating new ways of working

and driving scale and speed to deliver exponential growth. Focused and committed, and backed with the investment to succeed, we’re driving cross-company change to disrupt the entire industry. Ours is a place to innovate, take ownership and run with it. You’re trusted to explore and to find new solutions, experimenting with leading-edge technology and grappling with challenges in a modern technology environment that might never have been tackled before. It’s a dynamic and challenging environment to work in – but that’s why we like it. There are countless opportunities to learn and grow, whether that’s exploring new technologies in hackathons, or transforming the roles and work of colleagues, forever. Shape your own path, with support all the way. Diverse minds that work cross-functionally and inclusively together. Be part of a team that has the backing to innovate, disrupt an industry and change lives.

ABOUT THE ROLE?

We are looking for a cheminformatics scientist to tackle the most challenging informatics problems in the early drug discovery design-maketest- analyse (DMTA) process.

You will be part of a close-knit and technical team of informaticians, data scientists, machine learning and knowledge engineers, delivering data workflows and informatics solutions that will advance the standard of healthcare improving the lives of millions of patients across the globe. Your work will be applied to the full early science drug discovery project cycle to improve access to data, improve the quality and use of data and ultimately improve the quality of candidate drugs delivered out of all early research projects across AstraZeneca.

The ideal candidate will possess a blend of early discovery science skills (,e.g., chemistry, bioscience, DMPK, safety), will have several years of experience of informatics delivery in a scientific environment and will have successful experience of integrating workflows and building quality applications related to DMTA.

Key Accountabilities

  • Work closely within the team and with scientific colleagues across AstraZeneca early science units to ensure informatics and advanced analytics solutions meet the ongoing needs of all scientists.
  • Develop informatics solutions, e.g., using pipelining approaches, scripting and application integration to address key problems in the early science (DMTA) space.
  • Contribute to and potentially lead local and global science IT/informatics projects in DMTA space.
  • Understand and seek opportunities to apply artificial intelligence & machine learning to the world of chemistry and biology informatics
  • Seek solutions that streamline the data workflow across early science and ensure all scientists have access to the right data required to solve their key business problems at the right time.
  • Research external peers, academics and software providers to apply latest methods to relevant business problems.

Candidate Knowledge, Skills and Experience

  • Masters / PhD in (chem)informatics or a pharmaceutical scientific discipline or similar field with a proven record of informatics delivery in a pharmaceutical/biotech setting.
  • Strong coding and software engineering skills such as Python, Java, JavaScript, Scripting.
  • Experience working with relevant software and toolkits from vendors and providers such as Biovia, Perkin-Elmer, Chemaxon, Openeye, Dotmatics, Certara, Genedata, RDKit etc.
  • DMTA cycle pipelining experience, e.g., Pipeline Pilot or Knime,
  • Database and semantic skills and experience (e.g. Oracle, MySql, RDF/Triple stores/SPARQL, etc.)

WHY JOIN US?

We’re a network of entrepreneurial self-starters who contribute to something far bigger. There’s a diversity of expertise in our Technology group that’s unique to AstraZeneca – it allows us to dive deep into

exploring new leading-edge technology. We enable AstraZeneca to perform at its peak by delivering world-class technology and data solutions. Our work unlocks the potential of science. We optimise and evolutionise AstraZeneca by maximising efficiencies and finding new ways to drive productivity. From automation to data simplification. We’re not afraid to take ownership and run with it. Empowered with unrivalled freedom. A place to be open and transparent – we speak up, think creatively and share ideas. Our diverse contributions help us to make better decisions. But we have a constant drive to innovate,

and an appreciation for high standards. It takes challenging the status quo to add value in our ever-evolving environment. We love it here because put simply, we make a meaningful impact.

Technology at AstraZeneca is a home for purposeful disruptors!

SO, WHAT’S NEXT?

Are you already imagining yourself joining our team? Good, because we’d love to hear from you! Click the link to apply and we’ll be in touch as soon as we can.

WHERE CAN I FIND OUT MORE?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Competitive salary & benefits on offer.